dropping relationship vs disassociate

What are the differences between just drop/deleting the relationship though the CRM interface like on the image below:

if you click the X, it will delete the relationship

what happen there that would be different than using:

Moniker Moniker1 = new Moniker();
                Moniker1.Id = ID1.Value;
                Moniker1.Name = entity1name;
                Moniker Moniker2 = new Moniker();
                Moniker2.Id = ID2.Value;
                Moniker2.Name = entityname2;
                DisassociateEntitiesRequest mm = new DisassociateEntitiesRequest();
                mm.Moniker1 = Moniker1;
                mm.Moniker2 = Moniker2;
                mm.RelationshipName = relationshipname;
                DisassociateEntitiesResponse nnn = new DisassociateEntitiesResponse();

I have about 100k+ records on one relationship and just want to find a faster and supported way to delete it without side effects